TY - JOUR
T1 - Chemical constituents and antifungal activity of leaf essential oil from oreopanax ecuadorensis seem. (Pumamaki), endemic plant of Ecuador
AU - Noriega, Paco
AU - Vergara, Bryan
AU - Carillo, Carlos
AU - Mosquera, Tatiana
N1 - Publisher Copyright:
© 2019 Phcogj.Com.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Background: Oreopanax ecuadorensis Seem. is a plant from Ecuador, that is found in the Andean region of the country. The plant is commonly used in protective rituals, and as an anti-flu, analgesic and disinfectant medicine. Aim: The research aims to extract and analyze the chemical composition and evaluation of its antifungal potential of the essential oil extracted from its leaves. Methods: steam distillation was used for the extraction of essential oil, the evaluation of its components was performed by GC/MS, and the antifungal evaluation by the disc diffusion method. Results: The essential oil was obtained with a yield of 0.05%. 33 compounds were detected of which 30 were identified, corresponding to 99.28%; the most abundant molecules were: thujene <α-> (36.63%), followed by bicyclogermacrene with (8.76%), pinene <β-> with (8.32%) and limonene with 5.15%.Three of the four strains evaluated were affected by the oil at concentrations of 1.25%, inhibiting its growth. The strains were: Trichophyton mentagrophytes, Trichophyton rubrum and Microsporum canis. Conclusion: The essential oil shows good antifungal activity, which could be less than 1.25%. In this way, this medicinal plant is valued by verifying ancestral knowledge in the use of medicinal plants by the Andean people of Ecuador.
AB - Background: Oreopanax ecuadorensis Seem. is a plant from Ecuador, that is found in the Andean region of the country. The plant is commonly used in protective rituals, and as an anti-flu, analgesic and disinfectant medicine. Aim: The research aims to extract and analyze the chemical composition and evaluation of its antifungal potential of the essential oil extracted from its leaves. Methods: steam distillation was used for the extraction of essential oil, the evaluation of its components was performed by GC/MS, and the antifungal evaluation by the disc diffusion method. Results: The essential oil was obtained with a yield of 0.05%. 33 compounds were detected of which 30 were identified, corresponding to 99.28%; the most abundant molecules were: thujene <α-> (36.63%), followed by bicyclogermacrene with (8.76%), pinene <β-> with (8.32%) and limonene with 5.15%.Three of the four strains evaluated were affected by the oil at concentrations of 1.25%, inhibiting its growth. The strains were: Trichophyton mentagrophytes, Trichophyton rubrum and Microsporum canis. Conclusion: The essential oil shows good antifungal activity, which could be less than 1.25%. In this way, this medicinal plant is valued by verifying ancestral knowledge in the use of medicinal plants by the Andean people of Ecuador.
KW - Antifungal activity
KW - GC/MS
KW - Oreopanax ecuadorensis
KW - Puma Maki
UR - http://www.scopus.com/inward/record.url?scp=85077327679&partnerID=8YFLogxK
U2 - 10.5530/PJ.2019.11.236
DO - 10.5530/PJ.2019.11.236
M3 - Article
AN - SCOPUS:85077327679
SN - 0975-3575
VL - 11
SP - 1544
EP - 1548
JO - Pharmacognosy Journal
JF - Pharmacognosy Journal
IS - 6
ER -