Toxicological Evaluation of Essential Oil and Ethanolic Extracts of Ruta graveolens in Artemia salina

Mónica Espadero, Sandy Gavilanes, Tatiana Mosquera, Gabriela Alvarez

Resultado de la investigación: Capítulo del libro/informe/acta de congresoContribución de conferenciarevisión exhaustiva

Resumen

Traditional medicine is part of humanity’s cultural heritage and has been used for thousands of years to the present day. Different plants have extensive pharmacological activity, and it is used against various diseases, but the safe use of plants with pharmacological effects is still uncertain. R. graveolens is a specie known as medicinal plant since ancient times and currently used for treatment of various diseases, but at the same time, there are certain toxic components in its chemical composition. The toxicity of essential oil and ethanolic extracts at 50 and 96% of R. graveolens in Artemia salina was evaluated in this research. In addition, a qualitative comparison of the chemical components present in the essential oil and in the extracts was made by infrared spectroscopy (FT-IR). For the preparation of the extracts and the essential oil, flowers, leaves, and stems of the species previously dried were used, which were subjected to a process of maceration and distillation by steam drag, respectively, obtaining 0.13% yield of the essential oil. The FT-IR comparison of the essential oil with the spectra of 2-nonanone and 2-undecanone indicates the presence of C=O groups, C–H, C–C bonds, allowing the identification of ketones. For the toxicity test, the essential oil and the extracts at doses 0.1, 1, 10, and 100 ppm were used in A. salina for 24 h. Essential oil at concentrations > 10 ppm and ethanolic extract at concentrations > 25 ppm caused the death of more than 50% of individuals.

Idioma originalInglés
Título de la publicación alojadaCommunication, Smart Technologies and Innovation for Society - Proceedings of CITIS 2021
EditoresÁlvaro Rocha, Paulo Carlos López-López, Juan Pablo Salgado-Guerrero
EditorialSpringer Science and Business Media Deutschland GmbH
Páginas165-174
Número de páginas10
ISBN (versión impresa)9789811641251
DOI
EstadoPublicada - 2022
Evento7th International Conference on Science, Technology and Innovation for Society, CITIS 2021 - Virtual, Online
Duración: 26 may. 202128 may. 2021

Serie de la publicación

NombreSmart Innovation, Systems and Technologies
Volumen252
ISSN (versión impresa)2190-3018
ISSN (versión digital)2190-3026

Conferencia

Conferencia7th International Conference on Science, Technology and Innovation for Society, CITIS 2021
CiudadVirtual, Online
Período26/05/2128/05/21

Nota bibliográfica

Publisher Copyright:
© 2022, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

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