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Solitary Fibrous Tumour, a Rare Entity in the Parotid Gland: Case Report and Review of the Literature

  • Stephany Elizabeth Paladines Calle
  • , Ana Lirio Ramírez Ávila
  • , Jorge Eduardo Del Bosque Méndez
  • , Omar Antonio Soto Becerril
  • , Ana Laura Maldonado Tinajero
  • , Paola Estefani Gómez Castillo
  • , Mariana Terrazas Rubio
  • , Miguel Eduardo Ambrosio Sánchez
  • , Luis Alberto Gaitan Cepeda

Research output: Contribution to journalArticlepeer-review

Abstract

Solitary fibrous tumors are rare mesenchymal neoplasms of the oral cavity, and their occurrence in the salivary glands is uncommon. The purpose of this report is to present a case of solitary fibrous tumor originating in the parotid gland. In addition, a review of the scientific literature was conducted focusing on the clinicopathological characteristics of this neoplasm at the parotid gland level. We report the case of a 40-year-old female patient who presented with increased volume in the right parotid region. Histopathological examination revealed a proliferation of spindle-to-ovoid cells within a collagenized stroma, intermingled with hyalinized blood vessels showing a hemangiopericytoma-like pattern. Immunohistochemical analysis demonstrated strong expression of STAT6 and CD34. The literature review identified a total of 51 reported cases of solitary fibrous tumor involving the parotid gland. The mean age of affected patients was 51.5 years, with a slight female predominance (52.9%). The mean duration of lesion evolution was 31.7 months, ranging from 1 to 144 months. Solitary fibrous tumors of the parotid gland are rare entities that most often present as painless lesions with progressive enlargement. Surgical excision remains the treatment of choice, and the reported recurrence rate is relatively low.

Original languageEnglish
JournalJournal of Maxillofacial and Oral Surgery
DOIs
StateAccepted/In press - 2026

Bibliographical note

Publisher Copyright:
© The Association of Oral and Maxillofacial Surgeons of India 2026.

Keywords

  • Oral cavity
  • Parotid gland
  • Salivary gland
  • Solitary fibrous tumor

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