TY - JOUR
T1 - Solitary Fibrous Tumour, a Rare Entity in the Parotid Gland
T2 - Case Report and Review of the Literature
AU - Paladines Calle, Stephany Elizabeth
AU - Ramírez Ávila, Ana Lirio
AU - Del Bosque Méndez, Jorge Eduardo
AU - Soto Becerril, Omar Antonio
AU - Maldonado Tinajero, Ana Laura
AU - Gómez Castillo, Paola Estefani
AU - Terrazas Rubio, Mariana
AU - Ambrosio Sánchez, Miguel Eduardo
AU - Gaitan Cepeda, Luis Alberto
N1 - Publisher Copyright:
© The Association of Oral and Maxillofacial Surgeons of India 2026.
PY - 2026
Y1 - 2026
N2 - Solitary fibrous tumors are rare mesenchymal neoplasms of the oral cavity, and their occurrence in the salivary glands is uncommon. The purpose of this report is to present a case of solitary fibrous tumor originating in the parotid gland. In addition, a review of the scientific literature was conducted focusing on the clinicopathological characteristics of this neoplasm at the parotid gland level. We report the case of a 40-year-old female patient who presented with increased volume in the right parotid region. Histopathological examination revealed a proliferation of spindle-to-ovoid cells within a collagenized stroma, intermingled with hyalinized blood vessels showing a hemangiopericytoma-like pattern. Immunohistochemical analysis demonstrated strong expression of STAT6 and CD34. The literature review identified a total of 51 reported cases of solitary fibrous tumor involving the parotid gland. The mean age of affected patients was 51.5 years, with a slight female predominance (52.9%). The mean duration of lesion evolution was 31.7 months, ranging from 1 to 144 months. Solitary fibrous tumors of the parotid gland are rare entities that most often present as painless lesions with progressive enlargement. Surgical excision remains the treatment of choice, and the reported recurrence rate is relatively low.
AB - Solitary fibrous tumors are rare mesenchymal neoplasms of the oral cavity, and their occurrence in the salivary glands is uncommon. The purpose of this report is to present a case of solitary fibrous tumor originating in the parotid gland. In addition, a review of the scientific literature was conducted focusing on the clinicopathological characteristics of this neoplasm at the parotid gland level. We report the case of a 40-year-old female patient who presented with increased volume in the right parotid region. Histopathological examination revealed a proliferation of spindle-to-ovoid cells within a collagenized stroma, intermingled with hyalinized blood vessels showing a hemangiopericytoma-like pattern. Immunohistochemical analysis demonstrated strong expression of STAT6 and CD34. The literature review identified a total of 51 reported cases of solitary fibrous tumor involving the parotid gland. The mean age of affected patients was 51.5 years, with a slight female predominance (52.9%). The mean duration of lesion evolution was 31.7 months, ranging from 1 to 144 months. Solitary fibrous tumors of the parotid gland are rare entities that most often present as painless lesions with progressive enlargement. Surgical excision remains the treatment of choice, and the reported recurrence rate is relatively low.
KW - Oral cavity
KW - Parotid gland
KW - Salivary gland
KW - Solitary fibrous tumor
UR - https://www.scopus.com/pages/publications/105041394412
U2 - 10.1007/s12663-026-03110-9
DO - 10.1007/s12663-026-03110-9
M3 - Article
AN - SCOPUS:105041394412
SN - 0972-8279
JO - Journal of Maxillofacial and Oral Surgery
JF - Journal of Maxillofacial and Oral Surgery
ER -