TY - JOUR
T1 - Chemical composition and biological activity of five essential oils from the Ecuadorian Amazon rain forest
AU - Noriega, Paco
AU - Guerrini, Alessandra
AU - Sacchetti, Gianni
AU - Grandini, Alessandro
AU - Ankuash, Edwin
AU - Manfredini, Stefano
PY - 2019/4/25
Y1 - 2019/4/25
N2 - The chemical composition and biological activity of essential oils isolated from the leaves of Siparuna aspera, Siparuna macrotepala, Piper leticianum, Piper augustum and the rhizome of Hedychium coronarium were evaluated. These species are used medicinally in different ways by the Amazonian communities that live near the Kutukú mountain range. Chemical studies revealed that the main components for the two Siparuna species were germacrene D, bicyclogermacrene, α-pinene, δ-cadinene, δ-elemene, α-copaene and β-caryophyllene; for the two Piper species β-caryophyllene, germacrene D, α-(E,E)-farnesene, β-elemene, bicyclogermacrene, δ-cadinene and for H. coronarium 1,8-cineole, β-pinene, α-pinene and α-terpineol. The antioxidant activity of all essential oils was evaluated by 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2
0-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS), photochemiluminescence (PCL) quantitative assays, and DPPH and ABTS bioautographic profiles, with different results for each of them. Antimicrobial activity studies were carried out on three yeasts, six Gram positive and four Gram negative bacteria, by means of the disc diffusion method. The essential oil of H. coronarium showed the most relevant results on L. grayi, K. oxytoca and S. mutans, P. augustum and P. leticianum on S. mutans. An antibacterial bioautographic test for H. coronarium was also carried out and highlighted the potential activity of terpinen-4-ol and 1,8-cineole.
AB - The chemical composition and biological activity of essential oils isolated from the leaves of Siparuna aspera, Siparuna macrotepala, Piper leticianum, Piper augustum and the rhizome of Hedychium coronarium were evaluated. These species are used medicinally in different ways by the Amazonian communities that live near the Kutukú mountain range. Chemical studies revealed that the main components for the two Siparuna species were germacrene D, bicyclogermacrene, α-pinene, δ-cadinene, δ-elemene, α-copaene and β-caryophyllene; for the two Piper species β-caryophyllene, germacrene D, α-(E,E)-farnesene, β-elemene, bicyclogermacrene, δ-cadinene and for H. coronarium 1,8-cineole, β-pinene, α-pinene and α-terpineol. The antioxidant activity of all essential oils was evaluated by 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2
0-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS), photochemiluminescence (PCL) quantitative assays, and DPPH and ABTS bioautographic profiles, with different results for each of them. Antimicrobial activity studies were carried out on three yeasts, six Gram positive and four Gram negative bacteria, by means of the disc diffusion method. The essential oil of H. coronarium showed the most relevant results on L. grayi, K. oxytoca and S. mutans, P. augustum and P. leticianum on S. mutans. An antibacterial bioautographic test for H. coronarium was also carried out and highlighted the potential activity of terpinen-4-ol and 1,8-cineole.
KW - Amazonian essential oils
KW - Antimicrobial activity
KW - Antioxidant activity
KW - Biological activity
KW - GC-MS
KW - Monoterpenes/analysis
KW - Gram-Negative Bacteria/drug effects
KW - Rainforest
KW - Cyclohexenes/analysis
KW - Anti-Bacterial Agents/analysis
KW - Gram-Positive Bacteria/drug effects
KW - Microbial Sensitivity Tests
KW - Sesquiterpenes/analysis
KW - Zingiberaceae/chemistry
KW - Oils, Volatile/analysis
KW - Bridged Bicyclo Compounds/analysis
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85064830513&origin=inward
UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85064830513&origin=inward
UR - http://www.mendeley.com/research/chemical-composition-biological-activity-five-essential-oils-ecuadorian-amazon-rain-forest
U2 - 10.3390/molecules24081637
DO - 10.3390/molecules24081637
M3 - Article
C2 - 31027274
SN - 1420-3049
VL - 24
JO - Molecules
JF - Molecules
IS - 8
M1 - 1637
ER -