Chalcone-flavanone equilibrium in the isomeric mixture: 2',3,4,4',6'-Pentahydroxychalcone and eriodictyol from Stevia lucida

Pablo A. Chacon-Morales, Carolina Santiago-Dugarte, Juan M. Amaro-Luis

Research output: Contribution to journalArticlepeer-review

Abstract

From the leaves and stems of Stevia lucida Lagasca (Asteraceae), an equilibrium chalcone-flavanone isomeric mixture, composed of 2',3,4,4',6'-pentahydroxychalcone (8) (eriodictyol-chalcone) and eriodictyol (9) [ratio 8/9 5:3], was isolated as an isomorphic crystal. The mixture was structurally characterized by spectroscopic methods, including 1D- and 2D-NMR experiments. The presence of chalcones in the genus Stevia is reported here for the second time.

Original languageEnglish
Pages (from-to)89-96
Number of pages8
JournalAvances en Quimica
Volume15
Issue number3
StatePublished - 2020

Bibliographical note

Funding Information:
The authors are grateful to CDCHT-ULA for financial support (Grant C-1935-15-08-ED). Thank are also due to Eng. Juan Carmo-na Arzola, Department of Pharmacognosy and Organic Medicaments, Faculty of Pharmacy and Bioanalysis, University of Los Andes (ULA) for the identification of plant material. We also would like to thank Dr. Ángel E. Amesty, Instituto Universitario de Bio-Orgánica, Universidad de La Laguna. Tenerife, Spain, for the EI-MS.

Funding Information:
The authors are grateful to CDCHT-ULA for financial support (Grant C-1935-15-08-ED). Thank are also due to Eng. Juan Carmo-na Arzola, Department of Pharmacognosy and Organic Medica-ments, Faculty of Pharmacy and Bioanalysis, University of Los Andes (ULA) for the identification of plant material. We also would like to thank Dr. ?ngel E. Amesty, Instituto Universitario de Bio-Org?nica, Universidad de La Laguna. Tenerife, Spain, for the EI-MS.

Publisher Copyright:
© 2020, Universidad de Los Andes. All rights reserved.

Keywords

  • 2',3,4,4',6'-pentahydroxychalcone
  • Chalcones
  • Equilibrium mixture
  • Eriodictyol
  • Flavanones
  • Stevia

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