Evaluation of the Chemosystematics of Alkaloids, Phenolic Compounds, and Terpenes in a Medicinal Plant

This research project, led by the GIDCARB group, focuses on the chemical characterization of guayusa (Ilex guayusa Loes.), an ancestral medicinal plant from the Ecuadorian Amazon. Despite its growing commercial importance in the energy drink industry, there is a knowledge gap regarding how ecological variables (altitude, humidity, soil) affect its metabolic profile and bioactivity. The study will analyze 40 samples collected from various Amazonian locations using advanced techniques such as HPLC to quantify alkaloids, phenolic compounds, and terpenes, while also evaluating their antioxidant capacity. The problem addressed is the lack of raw material standardization, which limits the use of guayusa in higher value-added pharmaceutical and cosmetic sectors. By mapping the species' chemobiodiversity, the project seeks to provide essential technical information for growers and processors, fostering sustainable productive development. Expected results include the creation of a detailed metabolic map and the identification of correlations between the environment and metabolite production. This knowledge will allow for the diversification of bioproduct offerings, improving the income of local communities and promoting innovation in Ecuador's natural products industry.<br/><br/><b>Goal</b>: <br/>To evaluate the chemobiodiversity of guayusa (Ilex guayusa Loes.) in the Ecuadorian Amazon by analyzing its xanthine alkaloids, polyphenols, and terpenes to standardize its industrial potential. The study aims to determine how ecological variables influence the metabolic composition and antioxidant activity of the species.<br/><br/><b>Research lines</b>: <br/>Chemo-biodiversity