Recent research:
This body of work integrates clinical case studies and computational analyses to advance patient-specific cranial reconstruction using additive manufacturing and biomaterials. The research demonstrates that low-cost 3D printing of personalized anatomical models and cutting guides can reduce surgical time and morbidity, while enhancing precision and safety during craniotomies. Through finite element analyses and CAD-based design, customized PMMA- and composite-based cranial implants are evaluated for load distribution, fixation reliability, and neurocranial protection, confirming that tailored bone implants and their anchoring systems can safeguard internal structures without causing non-physiological harm. A forward-looking synthesis emphasizes a comprehensive methodology for design, manufacturing, and surgical planning of personalized bone implants, including the use of open-source tools and additively manufactured trial models to optimize outcomes. Overall, the work highlights the interdisciplinary convergence of biomedical engineering, materials science, and clinical epidemiology to improve reconstructive neurosurgery and material biocompatibility, while underscoring the potential of nano-hydroxyapatite composites and FEM-based simulations in guiding safer, cost-effective interventions.